Mechanism of antifungal action of kanosamine
نویسندگان
چکیده
منابع مشابه
Mechanism of antifungal action of kanosamine.
The antibiotic kanosamine inhibited growth of Saccharomyces cerevisiae and a range of human pathogenic fungi, including Candida albicans. Kanosamine was transported into C. albicans cells by the glucose transport system and subsequently phosphorylated. The product of its intracellular metabolism, kanosamine-6-phosphate, was an inhibitor of the enzyme glucosamine-6-phosphate synthase. Inhibition...
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ژورنال
عنوان ژورنال: Medical Mycology
سال: 2001
ISSN: 1369-3786
DOI: 10.1080/714031048